The researchers used high molecular weight compounds taken from a water-based dandelion extract and put them to the test in human HEK293-hACE2 kidney and A549-hACE2-TMPRSS2 lung cells. The dandelion blocked the protein-to-protein interactions between the S1 sub unit of the spike protein and the human ACE2 cell surface receptor.
Introducing Issue 42 of The NZ Journal of Natural Medicine
Highly relevant to contemporary concerns, Issue 42 features antiviral herbs that really work, of which Echinacea is just one important remedy. We are well aware of why they are often ignored and/or unjustifiably disparaged.
Our focus on nutrition highlights bromelain (an enzyme sourced from pineapple) as a potential option for Covid-19 and how the humble dandelion leaf (which can easily be incorporated into summer salads) may block spike proteins from SARS-CoV-2 from binding to the surface of cells and may therefore assist in the prevention or treatment of Covid-19.
In Vitro Effect of Taraxacum officinale Leaf Aqueous Extract on the Interaction between ACE2 Cell Surface Receptor and SARS-CoV-2 Spike Protein D614 and Four Mutants