Antibody-dependent Enhancement (ADE) and Vaccines

What is ADE?

ADE occurs when the antibodies generated during an immune response recognize and bind to a pathogen, but they are unable to prevent infection. Instead, these antibodies act as a “Trojan horse,” allowing the pathogen to get into cells and exacerbate the immune response.


edited_Antibody-dependent Enhancement (ADE) and Vaccines _ Children's Hospital of Philadelphia


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