Ivermectin, a potential anticancer drug derived from an antiparasitic drug

 

NIH National Library of Medicine

 

Ivermectin is a macrolide antiparasitic drug with a 16-membered ring that is widely used for the treatment of
many parasitic diseases such as river blindness, elephantiasis and scabies. Satoshi Omura and William C.
Campbell won the 2015 Nobel Prize in Physiology or Medicine for the discovery of the excellent efficacy of
ivermectin against parasitic diseases. Recently, ivermectin has been reported to inhibit the proliferation of
several tumor cells by regulating multiple signaling pathways. This suggests that ivermectin may be an anti-cancer drug with great potential

 

 

Ivermectin cancer

 

 

 

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Ivermectin inhibits HSP27 and potentiates efficacy of oncogene targeting in tumor models

Ivermectin has New Application in Inhibiting Colorectal Cancer Cell Growth

Anti-parasite drug ivermectin can suppress ovarian cancer by regulating lncRNA-EIF4A3-mRNA axes

Ivermectin converts cold tumors hot and synergizes with immune checkpoint blockade for treatment of breast cancer

 

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